Found 13 matching trials
Reducing Reconsolidation of Trauma Memories With Propranolol PHASE2 The purpose of this study is to test whether propranolol is capable of redu...
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Douglas Mental Health University Institute
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Effects of CBD Oil on Memory Reconsolidation and Trauma-Related Symptoms NA The purpose of this study is to investigate the effects of cannabidiol (CBD...
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The Laboratory for the Study of Anxiety Disorders, The University of Texas at Austin
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Treatment of Pediatric Post-traumatic Stress Disorder With Memory Reactivation Under the Influence of Propranolol PHASE3 By age 18, roughly 8% of traumatized youth have met criteria for a diagnosi...
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Toulouse University Hospital
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Treatment of PTSD by Reduction of Traumatic Memory Reconsolidation by Propranolol : a Multisite Trial PHASE2 The purpose of this study is to test whether propranolol, when given during...
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Centre Hospitalier Charles Perrens
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Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery PHASE4 The proposed R21 project will attempt to further develop a novel interventi...
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Massachusetts General Hospital Home Base Program
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Neuromodulation of the Hippocampus to Reduce Intrusive Re-Experiencing in PTSD: A Randomized Controlled Trial PHASE2 The goal of this clinical trial is to learn if non-invasive neurostimulatio...
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Tel Aviv University
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Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological Trauma PHASE2 The investigators propose to examine a mismatch-based method of reconsolida...
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Douglas Mental Health University Institute
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Tetris Intervention Following Subliminal Reactivation for Intrusive Memories NA Post-Traumatic Stress Disorder (PTSD) is characterized by recurrent, intrus...
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Multiple Locations
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Reconsolidation-Based Intervention for Traumatic Memories NA The goal of this clinical trial is to test the effect and underlying mechan...
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Multiple Locations
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Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD. PHASE2 Purpose: About 6.4% of the U.S. population suffers from posttraumatic stres...
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Massachusetts General Hospital
Treatments Being Tested
Experiment 1: Three-day aversive conditioning, extinction, and extinction retention testing paradigm Allopregnanolone (Allo) with 6% USP Dexolve (sulfobutyl ether-beta-cyclodextrin sodium salt) in 0.9% saline for IV infusion will be provided by the University of California, Davis, GMP manufacturer. Experiment 1. Three-day aversive conditioning, extinction, and extinction retention testing paradigm Matching IV Placebo Experiment 2. Three-day aversive conditioning, reconsolidation blockade, and testing paradigm Allopregnanolone (Allo) with 6% USP Dexolve (sulfobutyl ether-beta-cyclodextrin sodium salt) in 0.9% saline for IV infusion will be provided by the University of California, Davis, GMP manufacturer. Experiment 2. Three-day aversive conditioning, reconsolidation blockade, and testing paradigm Matching IV Placebo Learn More & Join Trial